Founder & CEO - Oncology Biotech (ADC/Cancer Stem Cell Therapy)
Location: U.S. or Europe | Type: Co-founder Opportunity
A preclinical biotech venture is seeking a Founder & CEO to lead development of a first-in-class protein drug conjugate (PDC) targeting cancer stem cells (CSCs)-a critical driver of metastasis, recurrence, and drug resistance.
The technology, based on natural ligands of LGR4/5/6 receptors, has shown strong anti-tumor activity in preclinical models of colorectal, ovarian, and gastric cancer. Backed by a prominent research foundation and supported by an experienced inventor, the company is poised for IND-enabling studies and first-in-human trials.
Responsibilities:Drive both dilutive and non-dilutive fundraising
Shape clinical and regulatory strategy
Oversee preclinical and IND-enabling activities
Build partnerships with CROs, CDMOs, pharma, and KOLs
Lead the company through early clinical development
Proven experience in biotech fundraising and leadership
Background in ADC or biologics development
Strong oncology network and scientific credibility
Familiarity with early-stage clinical and regulatory milestones
Equity-based co-founder role
Compensation tied to successful fundraising
Access to infrastructure and support from a broader venture-building ecosystem
This is a rare opportunity to lead a scientifically differentiated oncology company from inception through early clinical development.
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